锌指蛋白451抗体

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锌指蛋白451抗体


交货期:	1周
产品别名:	Anti-ZNF451 Anti-zinc finger protein 451 Antibody

产品介绍

靶标：

ZNF451

产品别名：

COASTER； ZATT； dJ417I1.1； ZNF451； zinc finger protein 451； zinc finger protein 451； E3 SUMO-protein ligase ZNF451； E3 SUMO-protein transferase ZNF451； coactivator for steroid receptors； zinc finger protein associated with TDP2 and TOP2；锌指蛋白451；

背景信息：

E3 SUMO-protein ligase; has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins. Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro. Required for MCM4 sumoylation (By similarity. Has no activity with SUMO1. Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11'. Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9'. Plays a role in regulating the transcription of AR targets.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。