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Rab11家族相互作用蛋白5抗体
产品介绍 靶标: RAB11FIP5 产品别名: GAF1; RIP11; gaf-1; pp75; rab11-FIP5; RAB11FIP5; RAB11 family interacting protein 5; RAB11 family interacting protein 5; rab11 family-interacting protein 5; RAB11 family interacting protein 5 (class I); gamma-SNAP-associated factor 1; phosphoprotein pp75; rab11-interacting protein Rip11; Rab11家族相互作用蛋白5; 背景信息: disease:Antibodies against RIP11 are found in sera from patients with systemic lupus erythematosus (SLE) or Sjoegren syndrome (SS), and in the sera from mothers of children with neonatal lupus erythematosus (NLE).,domain:Binds to vesicles enriched in neutral phospholipids via its C2 domain. The interaction is favored by Mg(2+) rather than Ca(2+).,function:Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane.,PTM:Phosphorylated on serine and threonine residues.,similarity:Contains 1 C2 domain.,subunit:Forms an heterooligomeric complex with RAB11FIP4. Binds NAPG and SSA2. Binds RAB11A that has been activated by GTP binding.,tissue specificity:Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas., 宿主:Rbt |
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