银牌会员第2
访问量: 2545696   网址: www.cnreagent.com/show1001160    在线留言 
产品搜索
蛋白质/抗原/多肽 >> 重组蛋白
重组转录因子HES4蛋白
重组转录因子HES4蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant HES4
Recombinant hes family bHLH transcription factor 4 protein
产品介绍
基因名:

HES4


产品别名:

bHLHb42; HES4; hes family bHLH transcription factor 4; hes family bHLH transcription factor 4; transcription factor HES-4; bHLH factor Hes4; class B basic helix-loop-helix protein 42; hHES4; hairy and enhancer of split 4; 转录因子HES4;


背景信息:
The Drosophila hairy and Enhancer of split genes encode basic helix-loop-helix (bHLH) transcriptional repressors that function in the Notch signaling pathway and control segmentation and neural development during embryogenesis. The mammalian homologues of Drosophila hairy and Enhancer of split are the HES gene family members, HES1-6, which also encode bHLH transcriptional repressors that regulate myogenesis and neurogenesis. The HES family members form a complex with TLE, the mammalian homologue of Groucho, and this interaction is mediated by the carboxy terminal WRPW motif of the HES proteins. The HES/TLE complex functions by directly binding to DNA, instead of interfering with activator proteins. Most HES family members, including HES1 and HES5, preferentially bind to the N box (CACNAG) as opposed to the E box (CANNTG). HES2 binds to both N and E box sites, while HES6 does not bind DNA. Rather, HES6 inhibits HES1 activity, thereby promoting transcription. HES1 and HES2 are expressed in a variety of adult and embryonic tissues. HES3 is expressed exclusively in cerebellar Purkinje cells, and HES5 is found solely in the nervous system. HES6 is produced in brain as well as in the limb buds of developing embryos.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

相关产品
我要咨询 关闭
  •      
  • 姓名* 
  • 电话* 
  • 单位* 
  • email 
  • 留言内容*
  • 验证码*  
  • 让更多商家关注