产品介绍 基因名： SLCO3A1 产品别名： OATP-D； OATP-RP3； OATP3A1； OATPD； OATPRP3； SLC21A11； SLCO3A1； solute carrier organic anion transporter family member 3A1； solute carrier organic anion transporter family member 3A1； solute carrier organic anion transporter family member 3A1； PGE1 transporter； organic anion transporter polypeptide-related protein 3； organic anion-transporting polypeptide D； sodium-independent organic anion transporter D； solute carrier family 21 (organic anion transporter), member 11； solute carrier family 21 member 11； 可溶性载质转运蛋白3A1； 背景信息： The organic anion transporter family of proteins mediate hepatic uptake of cardiac glycosides. OATP-D is a 710 amino acid member of the organic anion transporter protein family. As a multi-pass membrane protein, OATP-D mediates the Na+-independent transport of vasopressin, prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II and other organic anions, but not estrone-3-sulfate, DPDPE, taurocholate, DHEAS or digoxin. OATP-D is ubiquitously expressed with highest levels present in leukocytes and spleen. OATP-D is expressed as four isoforms produced by alternative splicing events. 标签：His-tag |
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