产品介绍 靶标： KIR2DL5B 产品别名： KIR2DL5； KIR2DL5.2； KIR2DLX； KIR2DL5B； killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5B； killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5B； killer cell immunoglobulin-like receptor 2DL5B； CD158 antigen-like family member F2； killer Ig receptor； killer cell immunoglobulin-like receptor 2DL5； killer cell immunoglobulin-like receptor 2DLX； killer cell immunoglobulin-like receptor two domains long cytoplasmic tail 5； killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B； killer-cell Ig-like receptor； 背景信息： killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5B(KIR2DL5B) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the 宿主：Rbt |
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