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干细胞转录因子NANOGP8抗体
产品介绍 靶标: NANOGP8 产品别名: NANOGP1; PN8; NANOGP8; Nanog homeobox retrogene P8; Nanog homeobox retrogene P8; homeobox protein NANOGP8; putative homeobox protein NANOGP8; 干细胞转录因子NANOGP8; 背景信息: This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009], 宿主:Rbt |
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