FAM21C蛋白抗体

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FAM21C蛋白抗体


交货期:	1周
产品别名:	Anti-WASHC2C Anti-WASH complex subunit 2C Antibody

产品介绍

靶标：

WASHC2C

产品别名：

FAM21A； FAM21C； VPEF； WASHC2C； WASH complex subunit 2C； WASH complex subunit 2C； WASH complex subunit 2C； WASH complex subunit FAM21C； family with sequence similarity 21 member C； vaccinia virus penetration factor； FAM21C蛋白；

背景信息：

Playing a essential role in the fission of tubules that serve as transport intermediates during endosome sorting, the WASH complex is present at the surface of endosomes and functions to recruit and activate the Arp2 3 complex for induction of actin polymerization. FAM21, Putative WASH complex subunit FAM21, is a component of the WASH complex. Having undergone evolutionary duplication, four highly homologous family members exist including FAM21A, FAM21B, FAM21C and FAM21D. FAM21 links the WASH complex to endosomes and is required for WASM-dependent retromer-mediated sorting. Also, by directly interacting with CapZ, FAM21 inhibits its anti-capping activity, thereby regulating actin dynamics.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。