DCN1样蛋白3抗体

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DCN1样蛋白3抗体


交货期:	1周
产品别名:	Anti-DCUN1D3 Anti-defective in cullin neddylation 1 domain containing 3 Antibody

产品介绍

靶标：

DCUN1D3

产品别名：

44M2.4； DCNL3； SCCRO3； DCUN1D3； defective in cullin neddylation 1 domain containing 3； defective in cullin neddylation 1 domain containing 3； DCN1-like protein 3； DCN1, defective in cullin neddylation 1, domain containing 3； DCUN1 domain-containing protein 3； defective in cullin neddylation protein 1-like protein 3； squamous cell carcinoma-related oncogene 3； DCN1样蛋白3；

背景信息：

Covalent attachment of NEDD8 to cullins, a process called neddylation, results in nuclear cullin accumulation, which promotes cell growth, migration, and transformation. DCUN1D3 inhibits neddylation of cullins by sequestering them to the plasma membrane, thereby promoting cell differentiation. Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane (PubMed:25349211). When overexpressed in transformed cells, may promote mesenchymal to epithelial-like changes and inhibit colony formation in soft agar (PubMed:25349211).

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。