JHDM1D蛋白抗体

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JHDM1D蛋白抗体


交货期:	1周
产品别名:	Anti-KDM7A Anti-lysine demethylase 7A Antibody

产品介绍

靶标：

KDM7A

产品别名：

JHDM1D； KDM7A； lysine demethylase 7A； lysine demethylase 7A； lysine-specific demethylase 7A； [histone H3]-dimethyl-L-lysine9 demethylase 7A； histone lysine demethylase JHDM1D； jmjC domain-containing histone demethylation protein 1D； jumonji C domain containing histone demethylase 1 homolog D； lysine (K)-specific demethylase 7A； lysine-specific demethylase 7； JHDM1D蛋白；

背景信息：

Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。