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跨膜蛋白174抗体
跨膜蛋白174抗体图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Anti-Tmem174
Anti-transmembrane protein 174 Antibody
产品介绍
靶标:

Tmem174


产品别名:

0610009B10Rik; AA986094; Tmem174; transmembrane protein 174; transmembrane protein 174; 跨膜蛋白174;


背景信息:
Transmembrane protein 174 (TMEM174) is a type III transmembrane protein with no clear signal peptide. The N and C terminals are located inside the cell. The core promoter region of the human TMEM174 gene is located within the region spanning -186 to +674 bp and that the transcription factors CREB and AP-1 are involved in the transcriptional regulation of this gene. TMEM174 is comprised of 243 amino acids and contains two predicted transmembrane helices which determine its subcellular localization in the endoplasmic reticulum and influences its functions. Over-expression of TMME174 enhanced the transcriptional activity of AP-1 and promoted cell proliferation, whereas the truncated mutant TMEM174DeltaTM without the transmembrane regions did not retain these functions. The TMEM174 gene exhibited high expression levels in certain renal carcinomas, which may indicate that TMEM174 may have a significant role in the development and progression of these renal carcinomas.

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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