锌指蛋白Zdhhc12抗体

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锌指蛋白Zdhhc12抗体


交货期:	1周
产品别名:	Anti-Zdhhc12 Anti-zinc finger, DHHC domain containing 12 Antibody

产品介绍

靶标：

Zdhhc12

产品别名：

1190004A01Rik； Zdhhc12； zinc finger, DHHC domain containing 12； zinc finger, DHHC domain containing 12； palmitoyltransferase ZDHHC12； DHHC domain-containing cysteine-rich protein 12； DHHC-12； probable palmitoyltransferase ZDHHC12； zinc finger DHHC domain-containing protein 12；锌指蛋白Zdhhc12；

背景信息：

ZDHHC12 (Zinc Finger DHHC-Type Palmitoyltransferase 12) is a Protein Coding gene. The ZDHHC12 gene, located on 9q34.11, is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, and frog. ZDHHC12 belongs to the DHHC palmitoyltransferase family. 3 alternatively spliced human isoforms have been reported. ZDHHC12 is widely expressed in the colon, stomach, and other tissues. ZDHHC12-mediated S-palmitoylation promotes the cell membrane localization of claudin-3 (CLDN3) and maintains its stability in ovarian cancer cells, contributing to the oncoprotein function of CLDN3. Targeting ZDHHC12-mediated CLDN3 S-palmitoylation might be a potential strategy for ovarian cancer therapy. 225 organisms have orthologs with the human gene ZDHHC12.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。