Pellino 2蛋白抗体

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Pellino 2蛋白抗体


交货期:	1周
产品别名:	Anti-PELI2 Anti-pellino E3 ubiquitin protein ligase family member 2 Antibody

产品介绍

靶标：

PELI2

产品别名：

PELI2； pellino E3 ubiquitin protein ligase family member 2； pellino E3 ubiquitin protein ligase family member 2； E3 ubiquitin-protein ligase pellino homolog 2； RING-type E3 ubiquitin transferase pellino homolog 2； pellino homolog 2； pellino-2； protein pellino homolog 2； Pellino 2蛋白；

背景信息：

PELI2 is a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. It is involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. It mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. It may be important for LPS- and IL1B-induced MAP3K7- dependent, but not MAP3K3-dependent, NF-kappa-B activation. And it can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。