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RHOT1抗体
产品介绍 靶标: RHOT1 产品别名: ARHT1; MIRO-1; MIRO1; RHOT1; ras homolog family member T1; ras homolog family member T1; mitochondrial Rho GTPase 1; mitochondrial Rho (MIRO) GTPase 1; rac-GTP binding protein-like protein; ras homolog gene family, member T1; 背景信息: Mitochondrial Rho GTPase 1 (MIRO1) is an enzyme that in humans is encoded by the RHOT1 gene on chromosome 17. The Ras homolog family member T1 (RHOT) is an atypical Rho Ca2+-binding GTPase that localizes to the mitochondria. RHOT1, the related protein RHOT2, the adaptor protein Milton, and the PTEN induced putative kinase 1 (PINK1), form a complex that is involved in axonal transport of mitochondria. Both PINK1 and Parkin target RHOT1 for phosphorylation and degradation, causing the arrest of mitochondrial motility. 宿主:Rbt |
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