膜相关环指蛋白1抗体

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膜相关环指蛋白1抗体


交货期:	1周
产品别名:	Anti-MARCHF1 Anti-membrane associated ring-CH-type finger 1 Antibody

产品介绍

靶标：

MARCHF1

产品别名：

MARCH-I； MARCH1； RNF171； MARCHF1； membrane associated ring-CH-type finger 1； membrane associated ring-CH-type finger 1； E3 ubiquitin-protein ligase MARCHF1； E3 ubiquitin-protein ligase MARCH1； RING finger protein 171； RING-type E3 ubiquitin transferase MARCH1； RING-type E3 ubiquitin transferase MARCHF1； membrane associated ring finger 1； membrane-associated RING finger protein 1； membrane-associated RING-CH protein I； membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase；膜相关环指蛋白1；

背景信息：

MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Thibodeau et al., 2008 [PubMed 18389477]; De Gassart et al., 2008 [PubMed 18305173]).[supplied by OMIM, Mar 2010],

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。