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Pacsin1抗体
产品介绍 靶标: Pacsin1 产品别名: A830061D09Rik; H74; mKIAA1379; syndapin; Pacsin1; protein kinase C and casein kinase substrate in neurons 1; protein kinase C and casein kinase substrate in neurons 1; protein kinase C and casein kinase substrate in neurons protein 1; Syndapin I; syndapin-1; 背景信息: Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT; this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization. Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex. Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length. Required for normal synaptic vesicle endocytosis; this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission (By similarity. Binds to membranes via its F-BAR domain and mediates membrane tubulation. 宿主:Rbt |
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