产品介绍 靶标： SRRM2 产品别名： 300-KD； CWF21； Cwc21； HSPC075； SRL300； SRm300； SRRM2； serine/arginine repetitive matrix 2； serine/arginine repetitive matrix 2； serine/arginine repetitive matrix protein 2； 300 kDa nuclear matrix antigen； RNA binding protein； SR-related nuclear matrix protein of 300 kDa； ser/Arg-related nuclear matrix protein of 300 kDa； serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa； splicing coactivator subunit SRm300； tax-responsive enhancer element-binding protein 803； taxREB803； testicular secretory protein Li 53； 丝氨酸/精氨酸相关核基质蛋白2； 背景信息： function:Part of pre- and post-splicing multiprotein mRNP complexes. May be involved in pre-mRNA processing events. Binds to RNA.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the CWC21 family.,subunit:Component of the active spliceosome. Found in a pre-mRNA splicing complex with SFRS4, SFRS5, SNRP70, SNRPA1, SRRM1 and SRRM2. Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8.,tissue specificity:Expressed in liver, placenta, and white blood cells., 宿主：Rbt |
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