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解整合素金属蛋白酶22(ADAM22)抗体
产品介绍 靶标: Adam22 产品别名: 2900022I03Rik; AI854032; MDC2; Adam22; a disintegrin and metallopeptidase domain 22; a disintegrin and metallopeptidase domain 22; disintegrin and metalloproteinase domain-containing protein 22; a disintegrin and metalloprotease domain (ADAM) 22; 解整合素金属蛋白酶22(ADAM22); 背景信息: ADAM metallopeptidase domain 22(ADAM22) Homo sapiens This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010], 宿主:Rbt |
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