USP20抗体

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USP20抗体


交货期:	1周
产品别名:	Anti-USP20 Anti-ubiquitin specific peptidase 20 Antibody

产品介绍

靶标：

USP20

产品别名：

LSFR3A； VDU2； hVDU2； USP20； ubiquitin specific peptidase 20； ubiquitin specific peptidase 20； ubiquitin carboxyl-terminal hydrolase 20； deubiquitinating enzyme 20； pVHL-interacting deubiquitinating enzyme 2； ubiquitin thioesterase 20； ubiquitin thiolesterase 20； ubiquitin-specific-processing protease 20；

背景信息：

This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013],

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。