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植烷酰辅酶A羟化酶2相互作用蛋白抗体
植烷酰辅酶A羟化酶2相互作用蛋白抗体图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Anti-PHYHIP
Anti-phytanoyl-CoA 2-hydroxylase interacting protein Antibody
产品介绍
靶标:

PHYHIP


产品别名:

DYRK1AP3; PAHX-AP; PAHXAP1; PHYHIP; phytanoyl-CoA 2-hydroxylase interacting protein; phytanoyl-CoA 2-hydroxylase interacting protein; phytanoyl-CoA hydroxylase-interacting protein; DYRK1A interacting protein 3; PAHX-AP1; phytanoyl-CoA alpha-hydroxylase associated protein; phytanoyl-CoA hydroxylase-associated protein 1; 植烷酰辅酶A羟化酶2相互作用蛋白;


背景信息:
PHYHIP (Phytanoyl-CoA hydroxylase-interacting protein) is a 330 amino acid protein that is strongly expressed in brain, with weak expression in ovary, small intestine and ovary. In transgenic mice, overexpression of PHYHIP in heart results in tachycardia and tachyarrhythmia. PHYHIP interacts with the Refsum disease gene product, PAHX, indicating that PHYHIP may play a role in the CNS deficits of Refsum disease, which is characterized by cerebellar degeneration, neurologic damage and peripheral neuropathies. PHYHIP also interacts with Dyrk1A, a protein that that is overexpressed in brain of Down-syndrome patients, therefore PHYHIP may participate in some of the neurological abnormalities of Down syndrome. Significantly, the gene encoding PHYHIP is localized to a region of the short arm of human chromosome 8 that is frequently found deleted in prostate, breast and several other types of cancers.

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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