产品介绍 靶标: TAF1C 产品别名: MGC:39976; SL1; TAFI110; TAFI95; TAF1C; TATA-box binding protein associated factor, RNA polymerase I subunit C; TATA-box binding protein associated factor, RNA polymerase I subunit C; TATA box-binding protein-associated factor RNA polymerase I subunit C; RNA polymerase I-specific TBP-associated factor 110 kDa; SL1, 110kD subunit; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box-binding protein-associated factor 1C; TATA-box binding protein associated factor, RNA polymerase I, C; TBP-associated factor 1C; transcription factor SL1; transcription initiation factor SL1/TIF-IB subunit C; TATA盒结合蛋白相关因子TAF1C; 背景信息: Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. 宿主:Rbt |
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