SCML1 Antibody (8-RY28) is a high quality monoclonal SCML1 antibody (also designated SCML1 antibody) suitable for the detection of the SCML1 protein of human origin. SCML1 Antibody (8-RY28) is available as the non-conjugated anti-SCML1 antibody. Putative Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. SCML1 (sex comb on midleg-like 1 (Drosophila)), is a 329 amino acid PcG protein belonging to the SCM family. Localizing to nucleus, SCML1 plays a role in testis development, spermatogenesis and embryonal development. While ubiquitously expressed, SCML1 is found at highest levels in adult skeletal muscle, heart and fetal liver. SCML1 contains one SAM (sterile alpha motif) domain and is encoded by a gene that spans 18 kb, contains 6 exons, maps to human chromosome Xp22.13, and is transcribed from telomere to centromere. Three SCML1 isoforms exist as a result of alternative splicing events.